基本信息
姓 名：庄静静
职 称：讲师
联系方式：zhuangjj929@sdu.edu.cn
教育及工作经历
2016.07-2018.12：山东大学（威海），微生物与生化药学，博士后
2013.12-至今：山东大学（威海），海洋学院，药学，讲师
2007-2013：华东理工大学（中国科学院上海药物研究所联合培养），药物化学，博士
2003-2007：华东理工大学，制药工程，学士
研究方向
基于HIFalpha为靶标化合物的筛选及其机制研究
海洋多糖的降解及其药理活性研究
主持的主要科研项目
1、中国博士后科学基金第61批面上资助，2017M612297，基于肠道微生物探究刺参多糖抗2型糖尿病作用及机制,2017/05-2018/12，主持
代表论文及著作
(1) Zhuang Jingjing; Zhang Keke; Liu Xiaohua; Liu Weizhi; Lyu Qianqian(*); Ji Aiguo(*), Characterization of a Novel PolyM-Preferred Alginate Lyase from Marine Vibrio splendidus OU02, Marine Drugs, 2018.8.22, 16(9)
(2) Shen Siqi(#); Hang Xudong(#); Zhuang Jingjing(#); Zhang Lin(*); Bi Hongkai(*); Zhang Liang(*), A back-door Phenylalanine coordinates the stepwise hexameric loading of acyl carrier protein by the fatty acid biosynthesis enzyme β-hydroxyacyl-acyl carrier protein dehydratase (FabZ), International Journal of Biological Macromolecules, 2019.1.22, 128: 5~11
(3) Zhou Tingting(#); Zhuang Jingjing(#); Wang Zhiwei; Zhou Yaodong; Li Wen; Wang Zhimin; Zhu Zhiyuan(*), Glaucocalyxin A as a natural product increases amyloid β clearance and decreases tau phosphorylation involving the mammalian target of rapamycin signaling pathway, NeuroReport, 2019.1.10, 30:310-316
(4) Tang Xuan(#); Zhuang Jingjing(#); Chen Jing(*); Yu Liang; Hu Lihong(*); Jiang Hualiang; Shen Xu(*), Arctigenin Efficiently Enhanced Sedentary Mice Treadmill Endurance, PLoS One, 2011.08.26, 6(8)
(5) Zhuang Jingjing; Zhang Haikun; Zhou Rong; Chen Lili; Chen Jing(*); Shen Xu(*), Regulation of prostaglandin F2α against β amyloid clearance and its inflammation induction through LXR/RXR heterodimer antagonism in microglia,Prostaglandins and Other Lipid Mediators, 2013.10.01, 106: 45~52
(6) Chen Xubing(#); Zhuang Jingjing(#); Liu Junhua; Lei Min; Ma Lei; Chen Jing(*); Shen Xu; Hu Li-hong(*), Potential AMPK activators of cucurbitane triterpenoids from Siraitia grosvenorii Swingle, Bioorganic & Medicinal Chemistry, 2011.10.1,19(19): 5776~5781
(7) Shen Sida(#); Zhuang Jingjing(#); Chen Yijia; Lei Min; Chen Jing; Shen Xu(*); Hu Lihong(*), Synthesis and biological evaluation of arctigenin ester and ether derivatives as activators of AMPK, Bioorganic & Medicinal Chemistry, 2013.7.1,21(13): 3882~3893
(8) 《营养药物概论》，科学技术出版社，参与编写
获奖情况
2017年山东大学教学比赛二等奖
2018年优秀本科生导师
